The ex-vivo and in-vivo models of drug delivery
Developing ex-vivo and in-vivo models of drug delivery in large animals such as pigs similar to humans
The nanovesicles as delivery vehicles
Developing extracellular vesicles as efficacious and safe carriers to deliver therapy-related substances to the inner ear.
The novel sensory receptors for drug delivery and immune response
Identifying novel sensory receptors and channels of round window membrane that sense chemicals, investigating how receptors and channels regulate drug passage to the inner ear, and harnessing receptors and channels to improve inner ear drug delivery.
3D high-resolution imaging for inner ear visualization and drug biodistribution.
In vivo and ex-vivo 3D high-resolution imaging for inner ear visualization, metabolomics, inflammation, and drug biodistribution.